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The Role of Cutibacterium Acnes in the Development of Degenerative Lumbar Intervertebral Disc Disease

Recruitingn/aAges 18 Years - anyAllMasaryk University
NCT07085247 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this study is to clarify the role of the bacterium Cutibacterium acnes in the development of degenerative disc disease in patients with lumbar disc herniation who underwent microdiscectomy as part of their regular medical care.

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📋 Eligibility rules (as published)
Inclusion Criteria: * minimum age of 18 years * MRI of the lumbosacral spine performed one month ± 2weeks before surgery showing a disc protrusion, herniation, or free nucleus pulposus sequestration * matching physical examination findings including positive straight leg raise test, dermatomal sensory deficits, myotome motor deficits, and diminished deep tendon reflexes. Exclusion Criteria: * antibiotics or corticosteroid use the month before surgery * ongoing bacterial or viral infection * immunocompromised patient * trauma * undefined radiological mass * inflammatory arthritis * other rheumatologic diseases.
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What it tests

  • Not listed
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Where

1 site
St. Anne´s University Hospital Brno
Brno, Czechia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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