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Methamphetamine Cue-reactivity

Recruitingn/aAges 18 Years - 60 YearsMaleIcahn School of Medicine at Mount Sinai
NCT07086014 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

In this observational cohort study, the researchers propose to first identify a psychophysiological marker of methamphetamine cue-reactivity and its incubation with abstinence from methamphetamine use (MUD) and examine group-differences between men who have sex with men (MSM) and non-MSM MUD. The primary objective is to identify psychophysiological markers of methamphetamine (MA) cue-reactivity and its abstinence incubation. The secondary objective is to examine group-differences in methamphetamine use disorder (MUD) individuals between homosexual men (MSM) and heterosexual men (non-MSM). The primary endpoint is to assess incubation of cue-reactivity longitudinally with its reduction in cognitive reappraisal, and the secondary endpoint is to examine the impact of cognitive reappraisal on clinical outcomes of methamphetamine use disorder (MUD) in homosexual men (MSM). 2-year long study.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Ability to understand and give informed consent * Identify as either MSM or non-MSM * Males; Age 18-60 * DSM-5 Diagnosis of MUD (Methamphetamine Use Disorder) * Have appropriate abstinence duration \[i.e., current Methamphetamine users (MA): 2 weeks (range: 1-3 weeks); MA-abstinent: 3 months (range: 2-4 months)\] * Treatment-seeking MUD must be in a treatment facility for substance use disorder, with MA as the primary drug (at the first visit) * Treatment-seeking MUD must be abstinent from MA use for approximately 2 weeks (range: 1-3 weeks) at enrollment. Exclusion Criteria: • Women
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What it tests

  • Cognitive Reappraisal
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Where

1 site
Icahn School of Medicine at Mount Sinai
New York, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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