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Effect of Cyanoacrylate Tissue Adhesive Versus Collagen Sponge on Palatal Donor Site Healing

RecruitingEARLY Phase 1Ages 18 Years - anyAllBeirut Arab University
NCT07086482 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if the use of cyanoacrylate glue (PeriAcryl) is effective in healing of the palatal donor site in adults requiring a free gingival graft. The main question\[s\] it aims to answer \[is/are\]: Does PeriAcryl accelerate the palatal tissue healing compared with the use of collagen sponge? Does PeriAcryl usage leave the patients more satisfied? Researcher will compare the outcomes of participants treated with PeriAcryl to those treated with collagen sponge to see if PeriAcryl accelerated the healing process of palatal tissues and led to fewer postoperative complications. Participants will: * be assigned to a study group using PeriAcryl or control group using Collagen sponge. * be followed-up to monitor healing and gather clinical information.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Low-moderate anesthetic risk (ASA I-II) * No restriction on ethnicity or gender * Patients requiring FGG from the palate for periodontal plastic surgery * Clinically healthy gingiva after phase I therapy * Full-mouth plaque index grades 0 and 1 * Bleeding scores \<15% Exclusion Criteria: * Patients who smoke \> 10 cigarettes/day * Patients with coagulation disorders * Systemic diseases * Patients on certain medications that may affect periodontal tissues * Pregnant and lactating patient * Patients with allergies to drugs that will be prescribed during the treatment phase * Pathological mental conditions (dementia, psychosis) and lack of cooperation * Excessive gag reflex
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What it tests

  • Cyanoacrylate tissue adhesive
  • Collagen sponge
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Where

1 site
Beirut Arab University
Beirut, Lebanon
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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