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Short-Term Nutritional Enhancement Combined With Health Education in Postoperative Colorectal Cancer Patients: A Randomized Controlled Trial

RecruitingNAAges 18 Years - anyAllXiaoqin Luo
NCT07087561 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This clinical study aims to evaluate whether short-term personalized nutritional support, when combined with structured health education, can improve nutritional status, quality of life, and clinical outcomes in patients who have undergone surgery for colorectal cancer (CRC). Colorectal cancer is one of the most common cancers worldwide, and many patients experience malnutrition and poor physical condition during treatment, which can negatively affect recovery and long-term survival. In this multicenter, randomized, controlled clinical trial, approximately 360 postoperative CRC patients will be enrolled and randomly assigned to one of four groups: (A) nutritional enhancement combined with health education, (B) health education alone, (C) nutritional enhancement alone, or (D) standard care (control group). Nutritional support will include individualized diet counseling and oral nutrition

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📋 Eligibility rules (as published)
Inclusion Criteria: * Signed informed consent * Age ≥ 18 years * Pathologically confirmed diagnosis of colon or rectal cancer * Mentally alert and capable of communication * Willing to participate in follow-up, with an estimated life expectancy of more than 6 months * Cancer stage IIa, IIb, or IIIa Exclusion Criteria: * Nutritional risk screening score of mPG-SGA \< 2 or NRS-2002 \< 3 * Diagnosed with AIDS * History of organ transplantation * Pregnant or breastfeeding women * Concurrent participation in another interventional clinical trial * Inability to care for oneself independently * Inability to engage in physical activity during the perioperative period * Severe comorbid conditions (e.g., uncontrolled cardiovascular disease, severe hepatic or renal dysfunction) * Known allergy or intolerance to components of the nutritional supplements used in the study
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What it tests

  • Personalized Oral Nutritional Supplementation
  • Personalized Parenteral Nutritional Supplementation
  • Structured Nutrition-Focused Health Education
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Where

1 site
Xi 'an Jiaotong University
Xi'an, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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