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Sleep Apnea Triggers of Atrial Fibrillation: N-of-1 Randomized Control Trial (SPARTA):

RecruitingNAAges 18 Years - 85 YearsAllThe Cleveland Clinic
NCT07087587 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

A pilot N-of-1 randomized controlled trial evaluating the effectiveness of a personalized CPAP intervention in reducing atrial fibrillation (AF) burden and improving AF-related quality of life in patients with moderate to severe obstructive sleep apnea (OSA).

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Informed consent 2. Age 18-85 years 3. High burden paroxysmal AF (≥1%) 4. Moderate-severe OSA (AHI ≥ 15) 5. Implanted device with atrial diagnostics 6. Enrolled in remote monitoring Exclusion Criteria: 1. AF ablation \<6 months 2. Valvular abnormalities 3. Excessive daytime sleepiness in safety-critical jobs 4. Plans for ablation during study 5. Non-CPAP OSA treatment 6. Recent device implantation (\<6 months) 7. Central sleep apnea
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What it tests

  • CPAP
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Where

2 sites
Cleveland Clinic
Cleveland, United States
University of Washington
Seattle, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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