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Efficacy of Gamma Auditory Stimulation for Cognitive Decline in Older Adults (Study 1)

RecruitingNAAges 60 Years - anyAllChang Gung Memorial Hospital
NCT07087951 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

Animal studies have shown that 40 Hz auditory stimulation alone can improve spatial memory and reduce Aฮฒ deposition. However, human studies using 40 Hz auditory stimulation alone remain limited. Therefore, this study will use a randomized, double-blind, placebo-controlled design to investigate the effects of 40 Hz auditory stimulation on cognitive function, EEG activity, sleep quality, and quality of life in older adults with mild cognitive impairment (MCI) or mild dementia.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: 1. Age over 60 years old. 2. MMSEโ‰ค 24 3. CDR scores of 0.5 and 1 4. Voluntary to sign the Informed Consent Form. Exclusion Criteria: 1. Diagnosis of other psychiatric or neurological disorders 2. Drug or alcohol addictions. 3. Serious heart, liver or kidney disorders, and visual, auditory or motor impairments interfering with neuropsychological tests. 4. History of clinical stroke, major depressive disorder or dysthymic disorder according to the DSM-5.
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What it tests

  • Gamma auditory stimulation device (active setting)
  • Gamma auditory stimulation device (sham setting)
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Where

1 site
Chang Gung University
Taoyuan, Taiwan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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