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Hysteroscopic Resection Versus Manual Vacuum Aspiration for Early Pregnancy

RecruitingNAAges 18 Years - 55 YearsFemaleUniversity Hospitals Cleveland Medical Center
NCT07088510 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Early pregnancy loss happens when a pregnancy that is not developing properly is found on an ultrasound before 12 weeks and 6 days. This type of loss occurs in about 10% of pregnancies. There are three main ways to treat this: waiting for it to pass naturally, using medication, or having surgery. Surgery is the most effective, working 99% of the time, compared to waiting (80% effective in 8 weeks) and medication (71-84% effective). Currently, surgery involves dilation of the cervix and curettage (removal of pregnancy tissue) with suction provided either from a manual hand-held pump or a machine. For the purposes of this study, a manual vacuum aspirator (or hand-held pump) will be used with ultrasound guidance. There is also another method called hysteroscopic resection, where the doctor uses a special camera to directly see and remove any pregnancy tissue from your uterus. Patients ofte

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult women age 18-55 * Ultrasound Diagnosis of Early Pregnancy Loss * \< 9 weeks gestational age as determined by ultrasound * Singleton non-viable pregnancy * Stated and willingness to comply with all study procedures and availability for the duration of the study * Provision of signed and dated informed consent form * Chose a surgical method of management for fetal loss Exclusion Criteria: * Pregnancy of Unknown Location * Current, viable pregnancy * Prior medical treatment for this early pregnancy loss * Contraindications to surgical management * Active infection (i.e. fever, chills, fundal tenderness) * Pre-existing coagulopathies
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What it tests

  • Hysteroscopic resection
  • Manual Vacuum Aspiration
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Where

1 site
University Hospitals
Cleveland, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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