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Single Step Protocol and Multi-step Warming Protocol for Blastocyst FET

RecruitingNAAges 18 Years - anyFemaleMแปน ฤแปฉc Hospital
NCT07088640 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

The multi-step thawing protocol with a reduction of non-permeable cryoprotectant concentrations to reduce osmotic shock caused by the rapid influx of water. Recent studies have shown that a simplified warming protocol by only a thawing solution gave a comparable survival rate but increased pregnancy rate, reduced patients' waiting time, and decreased the workload of embryologists.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Women aged from 18 * Undergoing no more than 3 previous IVF/ICSI cycles * Had at least a single good-quality blastocyst frozen. * Endometrium preparation using artificial cycle * Agree to single blastocyst transfer * Not participating in any interventional studies at the same time Exclusion Criteria: * Embryos from cycles after in-vitro maturation, pre-implantation genetic testing (PGT) * Having contraindications for exogenous hormone administration (e.g., breast cancer, thromboembolic disease) * Having uterine abnormalities (e.g., adenomyosis, intrauterine adhesions, unicornuate/ bicornuate/ arcuate uterus; unremoved hydrosalpinx or endometrial polyp)
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What it tests

  • Single-step warming protocol by thawing solution only
  • Standard warming protocol
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Where

1 site
My Duc Hospital
Ho Chi Minh City, Vietnam
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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