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The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery

RecruitingPhase 4Ages 18 Years - 70 YearsAllKing Abdullah International Medical Research Cent…
NCT07089251 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The aim of this clinical trial is to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative blood loss, thromboembolic complications, and hospitalization duration in patients undergoing knee joint arthroplasty. Also aim to evaluate the effect of administering low-dose epinephrine and tranexamic acid on perioperative thromboembolic complications, and hospitalization duration

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients undergoing knee joint arthroplasty. * Saudi and Non-Saudi Patient. * Patients who have Complete medical record. Exclusion Criteria: * End stage renal disease * Liver cirrhosis * Coagulopathy * Pre-operative Hgb \<10 5. * History of cerebrovascular accident or myocardial infarction in past 12 months. * History of Heart failure. * History of arrhythmia. * History of pheochromocytoma, thyrotoxicosis and glaucoma. * Pregnancy or breast feeding * History of Deep venous thrombosis or pulmonary embolism * Allergy to epinephrine or tranexamic acid
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What it tests

  • low-dose epinephrine and tranexamic acid
  • Tranexamic Acid (TXA) treatment
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Where

1 site
King Abdulaziz Medical City, Ministry of National Guard - Health Affairs
Riyadh, Saudi Arabia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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