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Surgical Outcomes and Complications of Posterior Spinal Fusion in Adolescent Idiopathic Scoliosis

Recruitingn/aAges 8 Years - 21 YearsAllAssiut University
NCT07092917 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Adolescent idiopathic scoliosis (AIS) is the most common form of scoliosis representing about 80-90% of all idiopathic scoliosis cases , characterized by lateral curvature of the spine of 10 degrees or more in children 10-18 years without underlaying cause . AIS affects 1-3% of adolescents globally . More common in females with a ratio of 8;1 (1) The exact cause of AIS remain unknown ,however it's thought to be multi factorial may be due to genetic predisposition as it's often familial with multiple genetic loci impacting its pathogenesis heritability range between 30-60% (2) Bio mechanically the asymmetrical growth of the vertebrae and spinal loading may lead to curvature progression during rapid growth spurts Some studies suggest that asymmetrical loading of the spine can progress the deformity. Multiple risk factors of progression have been detected: younger age at diagnosis , femal

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📋 Eligibility rules (as published)
Inclusion Criteria: * • Male and female Adolescents aged 10 to 18 years diagnosed with AIS * Patients with Risser sign 4 and 5 indicating maturity of the skeletal system * Patents with lenke classification system 2,3,4 * Curvature between 40 and 70 degrees Cobb angle indicating moderate to severe scoliosis suitable for surgical correction * Candidates for surgical intervention due to rapid progression of deformity more than 5 degrees per year ,functional limitations Exclusion Criteria: * • Congenital or neuromuscular scoliosis * Pre operative restrictive lung function * Previous spinal surgery * Severe co morbidities preventing surgical intervention .
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What it tests

  • Not listed
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Where

1 site
Assiut university hospitals
Asyut, Egypt
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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