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Driving Pressure Guided Mechanical Ventilation Versus Lung Protective Ventilation Among Patients Undergoing Elective Surgeries

RecruitingNAAges 16 Years - 80 YearsAllRawalpindi Medical College
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In plain words

What the trial is, and whether it could suit you

Patient undergoing surgeries in general anesthesia require support of their breathing by ventilator. Different strategies can be used to manage breathing of the patient. Lung protective ventilation provides breathing at a set volume determined by patient ideal body weight, along with a set rate to maintain adequate breathing. The pressures in the lower airway are kept less than 30 cm of H20 while a pressure of 5cm of H20 is applied to prevent lung collapse. Recently to above mentioned regimen a driving pressure is added which is a difference between lower airway pressure and pressure applied to prevent lung collapse. Ventilatory settings are adjusted to keep this driving pressure less than 15 cm of H2O.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * American Society of Anesthesiologists (ASA) class: I and II. * Elective laparoscopic surgeries requiring General Anesthesia and Mechanical ventilation * Patients receiving neuromuscular blockade during surgery. * Receiving Mechanical ventilation for at least 1h. Exclusion Criteria: * Pregnancy * Patients who had received mechanical ventilation of more than 1h in the previous 2 weeks. * Body mass index \>35 kg/m2 * Smokers and ASA class III and above. * Thoracic and Cardiac surgery
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What it tests

  • Lung protective ventilation
  • Driving pressure guided ventilation
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Where

1 site
Benazir Bhutto Hospital
Rawalpindi, Pakistan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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