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Quality Improvement Intervention for a Safe Antimicrobial Use Reduction in Critically Ill Patients

RecruitingNAAges 18 Years - anyAllHospital Sirio-Libanes
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn if an educational intervention with audit and feedback on physicians and health care professionals who participate in antimicrobial treatment decisions can reduce the use of antimicrobials in adult patients admitted to a sample of Brazilian intensive care units (ICUs). The educational intervention is based on a literature review of current recommendations for a more rational use of antimicrobials and microbiological tests in daily ICU practice. The main questions it aims to answer are: * Does the educational intervention reduce the antimicrobial consumption in the intensive care units? * Does this educational intervention aiming to reduce antimicrobial utilization in accordance with the latest guidelines have any safety signals regarding ICU mortality rates or ICU length-of-stay? Researchers will compare (1) ICUs sequentially randomized to t

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📋 Eligibility rules (as published)
Intensive care units inclusion Criteria: * ICU leadership acceptance to participant in the quality improvement intervention; * Hospital infection control leadership acceptance to participant in the quality improvement intervention; * ICU participation in the IMPACTO-MR platform with high quality data; * ICU potential for quality improvement based on a subjective assessment of the ICU and hospital infection leaderships Intensive care units exclusion Criteria: \- Absence of local IRB approval Participants inclusion Criteria: * All patients admitted to the intensive care unit Participants exclusion Criteria: * Patients younger than 18 years-old will be excluded from individual-level analysis
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What it tests

  • Educational Quality Improvement Intervention
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Where

9 sites
Hospital Maternidade São José
Colatina, Brazil
Santa Casa de Misericórdia de Passos
Passos, Brazil
Hospital Municipal de Maringá
Maringá, Brazil
Hospital Pelópidas Silveira
Recife, Brazil
Hospital Naval Marcílio Dias
Rio de Janeiro, Brazil
Hospital Onofre Lopes
Natal, Brazil
Hospital de Pronto Socorro
Porto Alegre, Brazil
Hospital Santa Cruz
Santa Cruz do Sul, Brazil

…and 1 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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