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Electroencephalogram in Patients With Friedreich's Ataxia for the Study of the Structural and Functional Connectome.

RecruitingNAAges 8 Years - 60 YearsAllIRCCS Eugenio Medea
NCT07095062 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Prospective, exploratory, multicenter pilot study investigating the structural and functional connectome in patients with Friedreich's Ataxia (FRDA) using high-density electroencephalogram (HD-EEG). The aim is to identify neurophysiological biomarkers and analyze the relationship between cortical connectivity, cognitive functioning, and clinical severity, particularly in response to rehabilitation treatment.

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📋 Eligibility rules (as published)
Inclusion criteria: * age between 8 and 60 years; * genetic diagnosis of FRDA: presence of guanine-adenine trinucleotide (GAA) expansion in the two alleles of the fratassin gene, GAA1 and GAA2; * score on the Scale for the Assessment and Rating of Ataxia (SARA) \< 30; * ability to take part in a neuropsychological assessment in Italian. Exclusion criteria: * age different from the range 8-60 years; * diagnosis of acquired ataxia or other genetic ataxias; * SARA scale score ≥ 30; * inability to take part in an Italian-language neuropsychological assessment
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What it tests

  • HD-EEG recordings, combined with cognitive and motor assessment
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Where

1 site
IRCCS Eugenio Medea / Associazione la Nostra Famiglia
Conegliano, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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