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A Long-term Extension Study of ORX750 in Participants With Narcolepsy and Idiopathic Hypersomnia

RecruitingPhase 2Ages 18 Years - 65 YearsAllCentessa Pharmaceuticals (UK) Limited
NCT07096674 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study is a long-term extension (LTE) of the parent Study ORX750 0201, and will provide long-term open-label safety, tolerability, and efficacy of ORX750 in participants with narcolepsy type 1 (NT1), narcolepsy type 2 (NT2), and idiopathic hypersomnia (IH).

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of narcolepsy (NT1 or NT2) or IH who was eligible for and completed the full treatment period in the eligible parent study ORX750-0201 (CRYSTAL-1) * Is willing and able to adhere to additional protocol requirements Exclusion Criteria: * Development of any new disease/disorder that in the opinion of the investigator would make the participant unable to continue the study * Unable to refrain from excluded medications, including those used for treatment of narcolepsy or idiopathic hypersomnia
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What it tests

  • ORX750
  • ORX750
  • ORX750
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Where

24 sites
Auburn, alabama
Auburn, United States
Santa Ana, California
Santa Ana, United States
Miami, Florida
Miami, United States
Orlando, Florida
Orlando, United States
Winter Park, FL
Winter Park, United States
Stockbridge, GA
Atlanta, United States
Atlanta, Georgia
Atlanta, United States
Sterling Heights, Michigan
Sterling Heights, United States

…and 16 more on ClinicalTrials.gov.

🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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