Point of Care Fibrinogen Measurement in Trauma Patients in the Emergency Department

Population (base) Adult trauma patients will be identified as follows: (1) by the trauma team leader on admission to the ED or (2) by the research team personnel following a massive transfusion protocol activation. Patients will be assessed for eligibility to enter the trial according to the criteria set out below. If patients are eligible for entry into the study following initial screening, they will be enrolled automatically under deferred consent. Patients will be considered eligible for enrolment in this trial if they fulfil all the inclusion criteria and none of the exclusion criteria detailed below. Inclusion criteria To be eligible to participate in this study, a subject must meet the following criteria: * The participant is judged to be an adult (according to the attending clinician, e.g. 16 years or older) and has sustained traumatic injury * The participant is deemed by the attending clinician to have on-going active hemorrhage * The major hemorrhage protocol (MTP) is activated or this patient and transfusion is initiated Exclusion criteria * A potential subject who meets any of the following criteria will be excluded from participation in this study: * The participant has been transferred from another hospital * The trauma team leader deems the injuries incompatible with life