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A Prediction Model in Pregnant Women With Aplastic Anemia

Recruitingn/aAges 20 Years - 50 YearsFemalePeking University People's Hospital
NCT07101770 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Aplastic anemia (AA) is a rare haematologic disorder characterized by bone marrow failure and pancytopenia. Its occurrence during pregnancy is exceedingly rare but poses significant risks, including maternal hemorrhage, infections, and perinatal complications such as preterm birth and fetal growth restriction. Consequently, pregnancy with AA is highly perilous for both mothers and infants. Early management is critical to ensure the health of both the mother and the baby. However, there are currently no predictive tools available to assess adverse outcomes in pregnant women with AA. Our center plans to conduct a multicenter, combined retrospective and prospective cohort study.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. pregnant women who had aplastic anemia before pregnancy 2. pregnant women with newly diagnosed aplastic anemia during pregnancy Exclusion Criteria: 1. age less than 20 years 2. without coagulation series results 3. termination of pregnancy before 20 weeks of gestation 4. multiple pregnancy
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What it tests

  • A combined retrospective and prospective observational follow-up
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Where

1 site
Peking University People's Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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