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โ† Trials
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HomeLink2: Reducing Posthospitalization Mortality Through Structured Home Care and Nutritional Support

RecruitingNAAges 18 Years - anyAllJohns Hopkins University
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In plain words

What the trial is, and whether it could suit you

People living with HIV (PLWH) are at high risk of poor health outcomes after being discharged from the hospital. This study is designed to test whether providing structured care at home-either with or without nutritional support-can help reduce the risk of death within six months of discharge and improve long-term health outcomes. The investigators are conducting a randomized clinical trial to evaluate the effectiveness of home-based care on post-hospital recovery. Participants are randomly assigned to one of three groups: (1) standard post-discharge care, (2) home-based care that includes medical assessments, support for taking HIV medications (adherence support), and psychosocial counseling, or (3) the same home-based care plus food parcels to support nutrition. This is a three-arm, individually randomized clinical trial and a type-1 hybrid implementation-effectiveness study, which m

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Documented HIV infection (either diagnosed during or prior to hospital admission), consisting of any clinical documentation, including a chart note of HIV positivity, Ritonavir-boosted darunavir (RVD) positivity, or antiretroviral therapy (ART) regimen documentation/prescription * โ‰ฅ18 years old as per hospital file or government issued document * Self-report that the participant resides within Matlosana sub-district * Admitted to an adult internal medicine ward at Tshepong Hospital * Have spent at least 2 nights in the hospital prior to recruitment to the trial. * Agree to post-discharge follow-up, including home visits * Are able to provide informed consent or if lacking capacity to provide consent at the time of recruitment, as determined by the study team, have a next of kin able to provide informed consent. Exclusion Criteria: * Admitted to a non-medical (i.e., surgical, psychiatric, etc.) ward, admitted for elective reasons, or admitted to facilitate onward transfer to another hospital * Participant or next of kin unable to provide written informed consent in any of the languages of the informed consents or spoken by the study team
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What it tests

  • HomeLink
  • HomeLink Plus Nutritional Support
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Where

1 site
Tshepong Hospital
Klerksdorp, South Africa
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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