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COMPARISON OF ZINC AND PROBIOTICS ON NEONATES WITH INDIRECT HYPERBILIRUBINEMIA UNDERGOING PHOTOTHERAPY

RecruitingPhase 2Ages 0 Days - 28 DaysAllQuaid-e-Azam Medical College
NCT07102836 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Study will evaluate effects of oral zinc and probiotics supplementation in neonates who have indirect hyperbilirubinemia and are receiving phototherapy. Aim is to compare efficacy of these two drugs in clearing bilirubin and reducing duration of phototherapy. Neonates will be randomly assigned to receive either drug alongside phototherapy.

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📋 Eligibility rules (as published)
Inclusion Criteria: * 1\. Term or Near term neonates 2. Age \<7 days at enrollment 3. Bilirubin levels within phototherapy range according to NICE bilirubin threshold charts 4. No identifiable pathology 5. Tolerating oral feeds 6. Parental or Guardian written informed consent taken. Exclusion Criteria: * 1\. Positive sepsis screen or clinical signs of infection 2. Direct hyperbilirubinemia 3. Gastrointestinal malformations 4. Oral intolerance 5. Requiring mechanical ventilation 6. Congenital anomalies 7. Parental or Guardian refusal to participate in study
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What it tests

  • Zinc sulfate
  • Probiotic lactobacillus rhamnosus GG
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Where

1 site
Sadiq Abbasi Hospital, QAMC, Bahawalpur
Bahawalpur, Pakistan
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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