🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Freeze-dried Bone Allograft vs Autologous Bone Blocks in the Lateral Augmentation of the Jaws

RecruitingNAAges 18 Years - anyAllSemmelweis University
NCT07104370 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

After tooth loss, the alveolar ridge undergoes various modeling and remodeling processes, resulting in overall bone resorption. In case of extensive alveolar atrophy, bone volume must be restored before or during implant placement to achieve successful dental rehabilitation and maximize implant survival and success rates. One possible method for reconstructing severe bone resorption is block bone augmentation. Due to its biological properties, autologous bone is considered the "gold standard" among bone graft materials, as it possesses osteoinductive, osteoconductive, and osteogenic properties. The advantages of using allografts over autologous bone grafts include reduced postoperative morbidity, decreased surgical time, and the absence of anatomical limitations regarding the amount of bone that can be harvested. The disadvantage of allografts is the loss of viable osteogenic cells and

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * over 18 years old * require lateral augmentation for implant rehabilitation Exclusion Criteria: * Smoking * Pregnancy * Poor oral hygiene * Failure to attend follow-up visits * Therapeutic-dose irradiation to the head and neck region * Local bone tumors, cysts, or inflammatory processes * Decompensated systemic diseases contraindicate surgery * Use of medications affecting bone metabolism (steroids, antiresorptive medications such as bisphosphonates, RANKL inhibitor antibodies, VEGF antagonists) * Psychiatric disorders contraindicate implant rehabilitation
💊

What it tests

  • Bone augmentation using an autologous bone block
  • Bone augmentation using freeze-dried allograft block
  • preoperative cone beam computed tomography (CBCT)
  • post-operative cone beam computed tomography (CBCT)
  • Dental implant placement
📍

Where

1 site
Semmelweis University Department of Public Dental Health
Budapest, Hungary
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy