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Comparative Experimental Study Between Bupivacaine and Ropivacaine Regarding Efficacy in Third Molar Removal Surgery Under General Anesthesia

RecruitingEARLY Phase 1Ages 18 Years - 60 YearsAllHenrique Tedesco
NCT07108465 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare the efficacy of bupivacaine and ropivacaine in third molar removal surgery under general anesthesia in healthy volunteers. The main question aims to determine whether there is any difference in vital signs, hemostasis and postoperative pain between ropivacaine and bupivacaine in patients undergoing third molars extraction under general anesthesia. Researchers will compare bupivacaine and ropivacaine in a split-mouth study to determine if one drug is more effective in third molar extraction surgery under general anesthesia (better hemostasis, less postoperative pain, and fewer changes in vital signs). Participants will undergo a single surgical procedure and complete the Visual Analog Scale to record postoperative pain

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged 18 to 60 * Patients ASA Physical Status Classification I and II * Patients with impacted or semi-impacted lower third molars with similar positioning on both sides according to the Pell and Gregory classification Exclusion Criteria: * Patients who can have surgery under local anesthesia * Patients where more procedures are required in the same surgical session
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What it tests

  • Bupivacaine 0,5%
  • Ropivacaine 0,75%
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Where

1 site
Hospital de Clínicas de Porto Alegre
Porto Alegre, Brazil
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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