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Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study

Recruitingn/aAges 18 Years - anyAllCopenhagen University Hospital, Rigshospitalet
NCT07110324 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Despite high success rates of hip and knee arthroplasty, up to 20% of patients report moderate-to-severe pain (NRS \> 3) persisting beyond the expected healing period. This investigator-initiated, descriptive cohort study will re-invite approximately 100 consenting patients with persistent postoperative pain-identified from a pool of \~7 000 respondents-to complete standardized assessments of neuropathic (DN4), nociplastic (IASP criteria + Fibromyalgia Survey Questionnaire) and nociceptive (KOOS/HOOS pain domains) pain. Primary outcomes are the prevalence of potential nociplastic pain and the proportion experiencing significant pain in two or more mechanistic categories. Secondary analyses will compare baseline vs. re-evaluated DN4 scores, FSQ and KOOS/HOOS distributions, and examine differences between patients with and without possible neuropathic pain. Findings will inform targeted pr

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📋 Eligibility rules (as published)
Inclusion Criteria: * All patients with persistent moderate-severe pain (NRS\>3) after THA, TKA and UKA * Acceptance to be contacted. Exclusion Criteria: * Re-operation * Luxation * Do not want to be contacted * Post-operative complications such as prosthesis infection, thromboembolism or fracture of the prosthesis.
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What it tests

  • Not listed
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Where

1 site
Rigshospitalet
Østerbro, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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