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Electroacupuncture and rTMS for Post-Stroke Motor Recovery

RecruitingNAAges 40 Years - 75 YearsAllJing Tao
NCT07113990 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study aims to evaluate the combined efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) and Electroacupuncture (EA) in improving motor function recovery post-stroke, compared to rTMS combined with sham EA. Participants will receive either active EA or sham EA alongside standard rTMS treatment. Outcomes will be assessed using standardized clinical scales and neuroimaging techniques to explore underlying neuroplasticity mechanisms.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Diagnosed with stroke confirmed by neuroimaging (CT/MRI). * First-ever stroke, unilateral hemispheric lesion, related to motor dysfunction. * Age between 40 and 75 years. * Duration from stroke onset between 2 weeks and 6 months. * Brunnstrom stage II-IV. * Right-handed. * Able to understand instructions and voluntarily provide written informed consent. Exclusion Criteria: * History of epilepsy or familial epilepsy. * Motor dysfunction due to non-vascular causes (e.g., tumor, trauma). * Severe aphasia or cognitive impairment (MoCA \< 18). * Severe systemic complications (e.g., severe organ dysfunction, deep vein thrombosis). * Presence of metallic implants or contraindications for MRI. * Severe anxiety (HAMA \> 7) or depression (HAMD \> 8). * Severe spasticity (modified Ashworth ≥ 2). * Fear or intolerance of TMS or electroacupuncture. * Pregnancy, breastfeeding, or concurrent participation in other clinical trials affecting outcomes.
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What it tests

  • Active EA
  • Sham EA
  • Active rTMS
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Where

3 sites
Fuzhou University Affiliated Provincial Hospital
Fuzhou, China
Fujian Provincial People's Hospital
Fuzhou, China
Wenzhou Hospital of Traditional Chinese Medicine
Wenzhou, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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