AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Steroids for Facial Nerve Function Protection in Post-surgical Vestibular Schwannoma Patients

RecruitingPhase 3Ages 18 Years - 70 YearsAllBeijing Tiantan Hospital
💬

In plain words

What the trial is, and whether it could suit you

The purpose of this study is to evaluate the efficacy and safety of steroids treatment compared with placebo in preserving facial nerve function after craniotomy in patients with vestibular schwannoma who have not received preoperative treatment and have good intraoperative facial nerve function.

Sign in to get the eligibility rules as simple questions to take to your doctor.

📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 70 years 2. Diagnosed with untreated unilateral vestibular schwannoma 3. No facial palsy before surgery (House-Brackmann grade I) 4. Intraoperative neurophysiological monitoring confirms good facial nerve function preservation, defined as: a)Post-tumor resection, evoked compound muscle action potential amplitude \>420 μV under 0.05 mA stimulation;and b)The amplitude is \>60% of baseline value measured before dural opening 5. Signed informed consent Exclusion Criteria: 1. Contraindications for craniotomy 2. Patients requiring corticosteroids during the perioperative period, or with known corticosteroid contraindications 3. Patients or first-degree relatives with a confirmed diagnosis of neurofibromatosis type 2 (NF2) 4. Karnofsky Performance Status (KPS) score \<90 before disease onset 5. Pregnant or planning to become pregnant during the study period 6. Participation in other interventional clinical trials 7. Judged unsuitable by the investigators
💊

What it tests

  • Steroids therapy
  • Placebo
📍

Where

1 site
Beijing Tiantan Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy