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Validation of RCC Predicting Model With Emulated-target Trial

Recruitingn/aAges 18 Years - 80 YearsAllPeking University Third Hospital
NCT07117227 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This single-center study utilizes real-world data (2012-2024) from 4700 renal cell carcinoma (RCC) patients at Peking University Third Hospital to: (1) Develop and validate a prognostic prediction model specifically for RCC patients, including those with venous tumor thrombus (VTT); (2) Compare the performance of this new model against existing RCC prediction models in both the overall RCC cohort and the VTT subgroup; (3) Employ an emulated target trial (ETT) methodology to evaluate whether risk-stratified treatment based on the prediction model (grouping patients as high/medium/low risk) improves survival outcomes .

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults ≥18 years of age; * Diagnosis of primary renal cell carcinoma before and during the surgery; * Received radical nephrectomy/nephron-sparing surgery. Exclusion Criteria: * Subjects with severely missing clinical information; * History of other malignant tumors. * Recurrence observed before first postoperative follow-up. * Discontinue the adjuvant treatment within in the first two course because of severe adverse react.
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What it tests

  • Model-guided adjuvant treatment
  • No adjuvant treatment
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Where

1 site
Peking University Third Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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