AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Ultrasonographic Assessment of Muscle Morphology, Function, and Clinical Findings in Spastic Cerebral Palsy

Recruitingn/aAges 4 Years - 18 YearsAllKocaeli University
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This study focuses on children with spastic cerebral palsy and aims to examine how muscle morphology and tissue characteristics, as assessed by ultrasound, may relate to functional motor abilities. It is designed as a prospective, cross-sectional, observational study. Planned ultrasound-based assessments include parameters such as muscle thickness, pennation angle, fascicle length, echo intensity, tissue stiffness (via shear wave elastography), and microvascular flow (via superb microvascular imaging). These measurements are intended to be compared with standard clinical evaluations, including the GMFCS, GMFM-66, MAS, MACS, and Tardieu Scale. The study seeks to contribute to a better understanding of the relationship between muscle architecture and functional outcomes, with the goal of generating insights that may inform individualized rehabilitation planning.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Diagnosis of spastic cerebral palsy (SCP) according to the criteria defined by Rosenbaum et al. (2007) * Age between 4 and 18 years * Gross Motor Function Classification System (GMFCS) Level I, II, or III * Manual Ability Classification System (MACS) Level I, II, III, or IV Exclusion Criteria: * Non-spastic types of cerebral palsy (e.g., dyskinetic, ataxic) * Diagnosis of neuromuscular disorders other than cerebral palsy (e.g., hereditary neuropathy, myopathy) * Presence of muscle contractures or fixed deformities in the limbs selected for ultrasound and clinical assessment * Cognitive or behavioral impairments that prevent cooperation during ultrasound or clinical evaluation * Botulinum toxin-A (BoNT-A) injection applied to the target muscles within the last 6 months * Current treatment with oral or intrathecal antispastic medications * History of orthopedic surgery or selective dorsal rhizotomy involving the target muscles * Acute infection, febrile illness, or severe systemic disease (e.g., advanced heart failure, respiratory insufficiency) that may compromise the safety of assessments
๐Ÿ’Š

What it tests

  • Not listed
๐Ÿ“

Where

1 site
Kocaeli University Faculty of Medicine
Kocaeli, Turkey (Tรผrkiye)
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy