AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

โ† Trials
๐Ÿงช

Impact of Cocaine Use and Withdrawal on Sleep

Recruitingn/aAges 18 Years - anyAllHรดpital le Vinatier
๐Ÿ’ฌ

In plain words

What the trial is, and whether it could suit you

This study investigates how cocaine use and withdrawal affect sleep and circadian rhythms in individuals undergoing inpatient detoxification. Using wearable sleep monitors, actigraphy, questionnaires, and hormonal biomarkers, it aims to capture both objective and subjective changes in sleep across three key stages: active use, early withdrawal, and late withdrawal. The study is unique in its ability to explore sleep microstructure, the circadian system's role via melatonin and cortisol measurements, and the dynamic relationship between subjective sleep perception and objective sleep data. It also examines whether sleep quality may serve as a predictive marker of long-term withdrawal success.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Male or female, aged 18 years or older * Meeting DSM-5 criteria for cocaine use disorder * Positive urine drug screen for cocaine * Scheduled for inpatient supervised cocaine detoxification within the next four weeks * Covered by a national health insurance plan or social security system * Have a valid, personal means of contact (telephone or email address) enabling remote follow-up at 6 months. Exclusion Criteria: * Current diagnosis of opioid use disorder or other psychostimulant use disorders (e.g., amphetamines, methamphetamines, cathinones, methylphenidate) * Unstable psychiatric disorder or somatic illness deemed incompatible with study participation by the investigator * Current treatment with methylphenidate, modafinil, solriamfetol, melatonin, pitolisant, naltrexone, or bupropion * Patients under legal guardianship * Pregnant or breastfeeding women: a pregnancy test will be performed prior to inclusion for women of childbearing potential * Individuals deprived of liberty by judicial or administrative decision
๐Ÿ’Š

What it tests

  • Multimodal Sleep and Biomarker Assessment
๐Ÿ“

Where

3 sites
Centre Hospitalier Le Vinatier
Bron, France
Centre Hospitalier Le Vinatier
Bron, France
CH Le Vinatier
Bron, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
๐Ÿ›ก๏ธ

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it โ€” not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use ยท Privacy