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โ† Trials
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Aging of the Vascular Wall

Recruitingn/aAges 18 Years - anyAllCentre Hospitalier Universitaire de Saint Etienne
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In plain words

What the trial is, and whether it could suit you

Demographic aging is predicted to be one of the most significant social changes of the 21st century. Aging is a slow, multifactorial process that progressively impacts the integrity of cells, tissues, and organs. This decline in function increases the risk of numerous diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases (CVD). CVD, the leading global cause of death, becomes more prevalent with age. Aging contributes to endothelial dysfunction, vessel stiffness, thickening, and impaired platelet function. These changes disrupt hemostatic processes and increase the risk of cardiovascular complications. Despite preventive strategies CVD remain a major public health challenge. Cellular aging, or senescence, affects all cell types, particularly endothelial cells and platelets. However, little research has compared the aging rates of different blood vessel types

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Major patients requiring coronary artery bypass grafting (CABG). Exclusion Criteria: * Hypertension, diabetes, systemic inflammatory disease.
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What it tests

  • Graft collection
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Where

1 site
CHU Saint-Etienne
Saint-Etienne, France
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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