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โ† Trials
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Sore Throat After Open Neck Elective Surgery

RecruitingPhase 4Ages 18 Years - anyAllSaint Petersburg State University, Russia
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In plain words

What the trial is, and whether it could suit you

This randomized clinical trial aims to evaluate the effectiveness of two medications-hydrocortisone ointment and lidocaine solution-applied to the endotracheal tube in reducing postoperative throat pain, hoarseness, and cough following thyroid or parathyroid surgery with neuromonitoring. A total of 764 adult patients undergoing elective neck surgery at Saint-Petersburg State University Hospital will be enrolled and randomly assigned to receive either a hydrocortisone-coated or lidocaine-coated endotracheal tube. Outcomes will be assessed upon awakening from anesthesia, at 24 hours, and again at 3 days postoperatively. The findings may contribute to improving postoperative comfort and recovery for patients undergoing similar surgical procedures.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Patients scheduled for elective open surgery on the thyroid/parathyroid glands with intraoperative neuromonitoring. * Age โ‰ฅ18 years. * Willing and able to provide voluntary informed consent for participation in the study. Exclusion Criteria: * Pregnancy (for women of childbearing potential). * Known allergy to hydrocortisone or lidocaine. * Refusal to participate in the study.
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What it tests

  • Hydrocortisone Acetate 1% Ointment
  • Lidocaine hydrochloride 0,05% with chlorhexidine
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Where

1 site
Saint Petersburg State University Hospital
Saint Petersburg, Russia
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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