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Health Oriented Protocol for Epidermal Radiodermatitis

Recruitingn/aAges 18 Years - anyAllFondazione Policlinico Universitario Agostino Gem…
NCT07129525 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Radiation therapy is a standard treatment for malignant tumors of the head and neck and pelvic regions, used alone or in combination with chemotherapy. While effective, it is often associated with adverse effects that can impact patient outcomes. Among the most frequent toxicities is radiation-induced dermatitis (RID), affecting up to 95% of patients. These skin reactions, ranging in severity, may compromise quality of life and lead to treatment interruptions.The severity of RID is influenced by both intrinsic and extrinsic factors. Intrinsic factors include age, sex, ethnicity, nutritional status, and comorbidities such as diabetes or systemic inflammation. Extrinsic factors include the radiation technique, total dose, treated volume, and presence of infections. These variables require close monitoring to reduce complications.Radiation damages the skin and underlying tissues, causing xe

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📋 Eligibility rules (as published)
Inclusion Criteria: * Patients aged ≥18 years * with head and neck or pelvic malignancies * undergoing either exclusive radiotherapy or concurrent chemoradiotherapy will be included, following signed informed consent. Exclusion Criteria: * Pediatric patients, * patients with malignancies outside the head and neck or pelvic regions, * patients who have not yet started or have already completed exclusive radiotherapy or concurrent chemoradiotherapy
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What it tests

  • Radiation therapy
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Where

1 site
Fondazione Policlinico Universitario Gemelli IRCCS
Roma, Italy
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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