🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Effect of Intravenous and Topical Tranexamic Acid on Drain Output in Breast Reduction Surgery

RecruitingPhase 4Ages 18 Years - anyFemaleMassachusetts General Hospital
NCT07131592 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

This study aims to evaluate whether tranexamic acid (TXA), a medication that helps reduce bleeding, can decrease fluid drainage after breast reduction surgery. Participants will be randomly assigned to receive either intravenous TXA or no TXA during surgery. Additionally, one breast will receive TXA through the surgical drain, while the other will receive saline. This approach allows to compare the effects of TXA on fluid buildup and healing. The goal is to improve recovery and reduce complications after breast reduction surgery.

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18 years or older * Elective bilateral breast reduction * Patient understands and is willing to participate in the study * Patient willing to and capable of providing informed consent Exclusion Criteria: * Age less than 18 years old * Prior radiation to the breast * Secondary/Revision breast reduction * Known coagulopathy or bleeding disorders * Intraoperative coagulopathy * History of seizures * Active smokers * Allergy or contraindication to TXA * Pregnant or breastfeeding patients * Patient is unable or unwilling to complete the anticipated study follow-up * Inability to understand the aims and objectives of the study * Inability to or unwilling to provide informed consent
💊

What it tests

  • IV TXA
  • Topical TXA
  • Topical saline
📍

Where

1 site
Massachusetts General Hospital
Boston, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy