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The Impacts of Chronic Non-specific Low Back Pain on Cognitive Functions of Older Adults: A Longitudinal Study

Recruitingn/aAges 60 Years - 85 YearsAllThe Hong Kong Polytechnic University
NCT07134699 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Chronic non-specific low back pain (CNSLBP) is a common condition among older adults and has been associated with an increased risk of executive function impairment. Research shows that older adults experiencing chronic pain are more likely to show worse cognitive performance compared to healthy individuals. While there is a bidirectional relationship between pain and executive functions, cognitive performance especially for some executive functions (e.g. inhibition, switching, working memory) is crucial for managing pain in older adults. Furthermore, executive dysfunctions are associated with decline in functional status among the population, particularly in performing instrumental activities in daily living. Therefore, maintaining executive function emerges as a pivotal consideration for older adults with CNSLBP. Studies provide preliminary evidence that connects brain changes with ch

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📋 Eligibility rules (as published)
Inclusion Criteria: * Older adults with and without chronic non-specific low back pain (CNSLBP) aged between 60 and 85 years * Having normal cognitive function (Hong Kong Montreal Cognitive Assessment ≥ 26)13 * Right-handed * Cantonese speaking * Having at least 6 years of formal education and know how to read and write Chinese * Agreeing to sign an informed consent form * Being able to communicate via email or text message because several study measures will be collected electronically. Exclusion Criteria: * Inability to ambulate without assistance from another person (canes or walkers will be allowed) * Having specific causes of LBP (e.g., spinal stenosis, lumbar disc herniation, spondylolisthesis, recent vertebral fracture, spinal infection) * Having other concurrent musculoskeletal conditions at other body parts (e.g., fibromyalgia, or neck or knee pain) * Self-reported history of lumbar or lower extremity surgery * Self-reported history of neurological or psychiatric disorders (e.g., stroke, brain surgery, head trauma; schizophrenia, multiple personality disorder, dissociative identity disorder, stroke) or self-reported cancer history * Self-reported specific inflammatory disorder: rheumatoid arthritis, rheumatica, scleroderma, lupus, or polymyositis * Unexplained, unintended weight loss of 20 lbs or more in the past year * Cauda equina syndrome * Uncorrected visual deficit * Drug or alcohol addiction * Taking alcohol, opioids or benzodiazepines medicines 24 hours before the experiment * Claustrophobia * Contraindications for undergoing the magnetic resonance imaging (MRI) examination based on the MRI safety screening form of University Research Facility in Behavioral and Systems Neuroscience at The Hong Kong Polytechnic University
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What it tests

  • Participants are not assigned an intervention
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Where

1 site
Department of Rehabilitation Sciences
Hong Kong, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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