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Optimizing Liver MRI Using Breath-Holding With and Without Oxygen

RecruitingNAAges 18 Years - 75 YearsAllUniversity of California, San Francisco
NCT07135401 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this interventional study (clinical trial) is to learn if different breath-holding techniques, with and without extra oxygen, can improve the quality of abdominal Magnetic Resonance Imaging (MRI) images in healthy adults, ages 18-75. The main questions it aims to answer are: * Does breath-holding at end-expiration improve image quality in abdominal MRI scans? * Does adding oxygen while breath-holding further reduce motion artifacts in abdominal MRI scans? Researchers will compare breath-holding with and without oxygen to see if using oxygen improves image quality during MRI scans. Participants will: * Be pre-screened for MRI safety and trained on breath-hold procedures * Have one non-contrast abdominal MRI scan at the University of California San Francisco (UCSF) China Basin Imaging Center * Use two different breath-holding techniques during the scan, with and without ox

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📋 Eligibility rules (as published)
Inclusion Criteria: * Subject must be within 18-75 years of age; * Subject must be able to hear and understand instructions without assistive devices; * Subject must provide written informed consent; * Subject has the necessary mental capacity to understand instructions, and is able to comply with protocol requirements; * Subject is able to remain still for duration of imaging procedure (approximately 30-45 minutes) Exclusion Criteria: * Subjects with a weight greater than 499 lbs; * Subjects that have metallic/conductive or electrically/magnetically active implants without Magnetic Resonance (MR) Safe or Magnetic Resonance (MR) Conditional labeling, with the exception of dental devices/fillings, surgical clips, and surgical staples determined to be safe for MRI scanning by a physician investigator; * Subjects that have implants with MR Unsafe labeling; * Subjects that have implants labeled as MR Conditional by the manufacturer for which the allowable conditions are not expected to be achieved by the MR environment or scan protocol; * Subjects who have a contraindication to MRI per the screening policy of the participating site; * Subjects with any respiratory or cardiovascular condition that could compromise safe breath holding; * Subjects who are female and pregnant
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What it tests

  • Breath-hold conditions
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Where

1 site
University of California, San Francisco
San Francisco, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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