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Mandibular Overdentures vs All-on-4 With PEEK

Recruitingn/aAges 40 Years - 70 YearsAllMenoufia University
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In plain words

What the trial is, and whether it could suit you

This study compares long-term peri-implant outcomes between two mandibular full-arch rehabilitation approaches-four-implant-retained overdentures and All-on-4 fixed prostheses-when both are fabricated with polyetheretherketone (PEEK) frameworks. While overdentures and All-on-4 prostheses are widely used, evidence on the clinical performance of PEEK frameworks in these modalities is scarce. By evaluating marginal bone loss and other peri-implant parameters, the research aims to clarify whether prosthetic design influences biological outcomes when using this high-performance polymer.

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: Adults aged โ‰ฅ40 years. Completely edentulous mandible for at least 6 months prior to implant placement. Treated with either: Four-implant-retained mandibular overdenture with a PEEK framework, or Mandibular All-on-4 fixed prosthesis with a PEEK framework. All implants placed in the lateral incisor and first premolar regions (per respective protocol). Restorations fabricated via CAD/CAM-milled PEEK framework with acrylic denture teeth. Prosthesis delivered with a delayed loading protocol. Minimum clinical and radiographic follow-up of 4 years. Availability of standardized baseline and follow-up periapical radiographs for marginal bone level assessment. Treated by the same surgical and prosthodontic team. Exclusion Criteria: History of uncontrolled systemic diseases that could affect bone healing (e.g., uncontrolled diabetes, osteoporosis under bisphosphonate therapy). History of head and neck radiotherapy. Active periodontal or peri-implant infection at the time of implant placement. Insufficient bone volume in the interforaminal region requiring grafting beyond minor augmentation. Heavy smoking habit (\>10 cigarettes/day) at the time of treatment. Parafunctional habits (e.g., severe bruxism or clenching) documented in patient records. Use of medications known to affect bone metabolism (e.g., high-dose corticosteroids, antiresorptive drugs). Pregnancy at the time of implant placement. Incomplete clinical or radiographic records. Follow-up period of less than 4 years.
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What it tests

  • Mandibular Four-Implant-Retained Overdenture (PEEK Framework); Mandibular All-on-4 Fixed Prosthesis (PEEK Framework)
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Where

1 site
Faculty of Dentistry
Shibฤซn al Kawm, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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