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Research on the Application of 99mTc-TCR-FAPI SPECT Imaging in Rheumatoid Arthritis

RecruitingNAAges 18 Years - 75 YearsAllLuo Yaping
NCT07138729 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study proposes to evaluate 99mTc-CTR-FAPI SPECT imaging as a cost-effective, low-radiation, and widely accessible alternative to 68Ga-FAPI PET/CT for assessing synovial lesions in RA patients, aiming to validate its diagnostic consistency with both PET/CT and physical examinations while correlating imaging findings with clinical disease activity metrics to establish a practical tool for long-term RA monitoring.

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age: 18-75 years old; 2. Meet the classification criteria for rheumatoid arthritis of the American College of Rheumatology/European Union for Rheumatology in 2010; 3. The highest disease activity in clinical practice (CDAI or SDAI score Exclusion Criteria: 1. Patients with other autoimmune diseases; 2. Patients with concurrent tumors; 3. Women who are pregnant or planning to become pregnant, women in the preconception period, pregnant and lactating women, and women with child-rearing plans during the study period; Subjects of childbearing age need to take effective contraceptive measures during the research process; 4. Active infection 5. Suffering from claustrophobia or other mental disorders, with poor compliance resulting in inability to cooperate with this researcher; (6) Situations where other researchers consider it inappropriate to participate in this clinical trial.
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What it tests

  • 68Ga-FAPI PET/CT and 99mTc-CTR-FAPI SPECT
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Where

1 site
Peking Union Medical College Hospital
Beijing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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