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Combined Injury-site & Lumbosacral Epidural Spinal Cord Stimulation

RecruitingNAAges 18 Years - 70 YearsAllThe University of Hong Kong
NCT07139496 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Spinal cord stimulation (SCS) has been shown in previous studies to be capable of restoring motor and autonomic function in patients with chronic complete spinal cord injury (SCI). Clinical studies have demonstrated that SCS enables activation of previously paralyzed muscles, leading to functional improvements in patients in the chronic stage of paralysis through the delivery of activity-based interventions. For most previous studies on SCS in SCI, stimulation was invariably applied to lumbrosacral plexus only. In this study, after signing the consent form, the patient will be assigned for standard surgery with additional implant of the spinal cord stimulator. The investigators propose to conduct the SCS with three phases. For the first phase, SCS over lumbrosacral spinal cord will be activated for 3 months with appropriate stimulation of lower limb muscles for walking together with phys

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. American Society of Anesthesiologist (ASA) status I-III 2. Age 18-70 years old 3. Patients with SCI more than 2 years 4. Traumatic or atraumatic spinal cord injury 5. American Spinal Injury Association (ASIA) Impairment Scale A and B 6. Have previous MRI to document extent of spinal cord injury before recruitment Exclusion Criteria: 1. Chronic opioid user 2. Presence of chronic pain condition (pain duration over 3 months) 3. Alcohol or substance abuse 4. active and unaddressed psychiatric diseases
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What it tests

  • Spinal Cord Stimulator
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Where

1 site
Queen Mary Hospital
Hong Kong, Hong Kong
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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