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Zinc as an Adjunctive Therapy for Cervical Dystonia

RecruitingPhase 2Ages 18 Years - 89 YearsAllUniversity of Florida
NCT07140874 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to evaluate if supplemental zinc can prolong the duration of benefit of botulinum toxin injections in cervical dystonia patients receiving care at the University of Florida. The main aims are: 1. To evaluate the efficacy of zinc citrate supplementation in prolonging the duration of symptom relief provided by botulinum toxin type A (Botox) injections in cervical dystonia patients. 2. To assess the safety and tolerability of zinc supplementation in this patient population. 3. To analyze the potential influence of zinc supplementation on the quality of life and functional outcomes in cervical dystonia patients receiving Botox. Researchers will compare zinc citrate to a placebo (a look-alike substance that contains no active drug) to see if zinc works to extend the effects of Botox. Participants will: Take zinc citrate or a placebo every day for 3 mont

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adults aged 18-89 years. * Diagnosed with cervical dystonia. * Receiving regular BoNT type A (Botox) injections for at least six months. Exclusion Criteria: * Known allergy or intolerance to zinc. * Significant comorbidities or concurrent medications that could interfere with study outcomes. * Pregnant or breastfeeding women. * Already taking a zinc supplement which would exceed tolerable upper intake level in adults (40 mg elemental zinc per day) with addition of zinc study supplement.
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What it tests

  • Zinc citrate
  • Placebo
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Where

1 site
Norman Fixel Institute for Neurological Diseases
Gainesville, United States
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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