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Application of the "Off-Clamp And Sutureless" Technique in Robot-Assisted Partial Nephrectomy

RecruitingNAAges 18 Years - 80 YearsAllShao Pengfei
NCT07141225 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The detection rate of renal masses smaller than 7 cm has significantly increased in recent years. To preserve postoperative renal function to the greatest extent possible, guidelines from the European Association of Urology (EAU), the National Comprehensive Cancer Network (NCCN), and others have endorsed partial nephrectomy (PN) as the preferred treatment strategy for small renal masses. In conventional PN, it is necessary to clamp the renal artery or its branch arteries and employ a double-layer suturing technique to close the resection bed. This controls bleeding, maintains a clear surgical field, and prevents postoperative urinary leakage. The maximum safe duration of warm ischemia to avoid irreversible renal parenchymal damage remains controversial, though most studies indicate a window of 20-30 minutes. Consequently, the "off-clamp sutureless" concept has gained prominence. Its cor

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📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age between 18 and 80 years old, regardless of gender; 2. Radiological findings demonstrating a tumor size of ≤7 cm; 3. Imaging studies showing no evidence of collecting system invasion; 4. Scheduled to undergo robot-assisted partial nephrectomy (RAPN). Exclusion Criteria: 1. Preoperative imaging demonstrating evidence of distant metastasis or lymph node involvement; 2. Unilateral or bilateral multiple lesions not amenable to simultaneous resection; 3. History of prior systemic therapy, including molecular targeted therapy, immunotherapy, or chemotherapy; 4. Intraoperative conversion to radical nephrectomy; 5. Intraoperative conversion to open surgery.
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What it tests

  • Off-Clamp Sutureless Technique
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Where

1 site
The First Affiliated Hospital of Nanjing Medical University (Jiangsu Provincial People's Hospital)
Nanjing, China
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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