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Electroporation vs. Radiofrequency Ablation Guided by 3D Imaging in Repeat Procedures for Atrial Fibrillation

RecruitingNAAges 18 Years - 85 YearsAllWroclaw Medical University
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In plain words

What the trial is, and whether it could suit you

This is a prospective, randomized clinical trial evaluating the efficacy and safety of two techniques for repeat catheter ablation in patients with recurrent atrial fibrillation (AF): thermal energy ablation (radiofrequency) and non-thermal electroporation (pulsed field ablation), both guided by 3D imaging systems. Patients undergoing repeat AF ablation will be randomly assigned to receive either thermal or electroporation ablation, performed according to standard hospital protocols. No additional invasive procedures are required. Following the ablation, participants will attend follow-up visits at 3, 6, and 12 months, including medical history review, physical examination, 12-lead ECG, and 24-hour Holter monitoring. Unscheduled ECG assessments will also be available if arrhythmia symptoms occur. All study-related procedures are non-invasive and align with routine post-ablation care. R

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: Documented recurrence of AF or atypical atrial flutter after prior PVI Eligibility for re-PVI Exclusion Criteria: Left ventricular ejection fraction \< 30% Left atrial volume index (LAVI) \> 72 mL/mยฒ Untreated hyperthyroidism Hypertrophic cardiomyopathy Severe valvular heart disease
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What it tests

  • Pulsed field ablation of reccurent atrial arrythmia
  • Radiofrequency ablation of reccurent atrial arrythmia (standard of care)
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Where

1 site
Clinical Department of Cardio, Jan Mikulicz Radecki University Hospital in Wroclaw
Wroclaw, Poland
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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