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Hematological Markers MPV, PLR, and NLR in Primary Versus Secondary Antiphospholipid Syndrome

Recruitingn/aAges 18 Years - anyAllNew Valley University
NCT07142239 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

Antiphospholipid syndrome is a thrombo-inflammatory autoimmune disorder with a complex antiphospholipid antibody-mediated pathogenesis, and high heterogeneity in clinical presentation and disease course. Clinical presentation in antiphospholipid syndrome includes venous and arterial thrombosis, pregnancy complications, and a broad range of microvascular and non-thrombotic manifestations

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Adults (age โ‰ฅ18 years) * Diagnosis of APS based on updated Sydney classification criteria confirmed by: Clinical history of thrombosis and/or pregnancy morbidity, Persistent presence (โ‰ฅ12 weeks) of antiphospholipid antibodies (aCL, anti-ฮฒ2-glycoprotein I, and/or lupus anticoagulant) Exclusion criteria: * Current infection or inflammatory condition unrelated to APS * Hematological malignancies or other blood disorders * Recent blood transfusion or platelet-altering medications other than APS treatments
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What it tests

  • โ€ข Complete blood count , MPV
  • Calculation of PLR: Platelet count / Lymphocyte count and Calculation of NLR:
  • Antiphospholipid antibody profile
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Where

1 site
New Valley University
Al Khฤrjah, Egypt
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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