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Epidemiology and Biomarker Study in Alzheimer's Disease

RecruitingPhase 3Ages 55 Years - 75 YearsAllEli Lilly and Company
NCT07142954 on ClinicalTrials.gov โ†—
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In plain words

What the trial is, and whether it could suit you

Study AACU determines rates of cognitive worsening in participants within elevated and not elevated plasma P-tau217 cohorts. Participation in AACU will last approximately 7 years.

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๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * The participant must self-report unimpaired cognition. * The participant must have adequate literacy, vision, and hearing for neuropsychological assessments at the time of screening. Exclusion Criteria: * Have seen a doctor about memory concerns. * Have a history or diagnosis of cognitive impairment, or significant other neurodegenerative disease that can affect cognition. * Are currently enrolled or have previously participated in any Alzheimer's Disease (AD)-related study involving an investigational drug intervention. * Are currently using or have previously used prescription medications for treatment of mild cognitive impairment (MCI) or dementia such as amyloid targeting therapy (that is, lecanemab, donanemab, aducanumab), cholinesterase inhibitors (for example, benzgalantamine, donepezil, galantamine, rivastigmine), and memantine.
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What it tests

  • P-tau217 Test
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Where

4 sites
Care Access - Houston
Houston, United States
The University of Tokyo Hospital
Bunkyล City, Japan
Souseikai Sumida Hospital
Tokyo, Japan
Higashi Shinjuku Clinic
Tokyo, Japan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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