🌐 EnglishEN

AI Cure is a research tool showing open data. Not medical advice. Discuss with your doctor. Terms

← Trials
🧪

Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism

RecruitingNAAges 18 Years - anyAllInsel Gruppe AG, University Hospital Bern
NCT07143539 on ClinicalTrials.gov ↗
💬

In plain words

What the trial is, and whether it could suit you

Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with anticoagulation (blood thinners). The randomized RehabPE trial investigates whether an early, structured rehabilitation program with physical training and patient education can prevent such long-term effects. The study includes hospitalized patients with acute symptomatic PE who are at increased risk of impaired quality of life three months after diagnosis. After informed consent, patients are randomly assigned to one of two groups: one receives an early 6-8-week, center-based rehabilitation program; the other receives standard follow-up care without rehabilitation. The intervention group completes 16-18 outpatient sessions of endurance and strength training, along wit

Sign in to get the eligibility rules as simple questions to take to your doctor.

Sign in
📋 Eligibility rules (as published)
Inclusion Criteria: 1. Age ≥18 years 2. Hospitalization for objectively confirmed acute symptomatic PE, defined as intraluminal filling defect of a segmental or more proximal pulmonary artery on computed tomography pulmonary angiography (CTPA) or a high-probability ventilation-perfusion scintigraphy, and admission within the past 7 days 3. Increased risk for post-PE syndrome, defined as simplified Pulmonary Embolism Severity Index (sPESI) ≥1 point at the time of admission 4. Written informed consent Exclusion Criteria: 1. Contraindication to EBR (known unstable cardiac conditions like angina pectoris, severe valvular heart disease, or severe resting pulmonary hypertension) 2. Medical condition that clearly precludes participation in EBR (e.g., inability to walk, unstable joints, severe neurological impairment) 3. Recently completed (i.e., \<6 months), ongoing, or planned in- or outpatient EBR, or planned supervised outpatient physiotherapy for any indication 4. Planned hospitalization during follow-up (e.g., elective surgery or inpatient chemotherapy) 5. Contraindication to anticoagulation 6. Life expectancy \<1 year based on the treating physician's clinical judgement 7. Known pregnancy 8. Inability to speak German or French 9. Participation in another study that prohibits concurrent participation in RehabPE 10. Unable to provide informed consent (e.g., due to dementia) 11. Unwilling to provide informed consent 12. Prior enrollment in this study
💊

What it tests

  • Exercise-based rehabilitation program
📍

Where

6 sites
Cantonal Hospital Aarau
Aarau, Switzerland
Cantonal Hospital Baden
Baden, Switzerland
Inselspital, Bern University Hospital
Bern, Switzerland
Geneva University Hospitals
Geneva, Switzerland
Lausanne University Hospital
Lausanne, Switzerland
University Hospital Zürich
Zurich, Switzerland
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
🛡️

AI Cure shows public evidence (Open Targets, ClinicalTrials.gov, PubMed, openFDA, DepMap, AlphaFold) with its source, and AI summaries that cite it — not medical advice and not a cure. Treatment decisions belong with your doctor. Research ideas are shared only with approved researchers and labs, who can test them. In an emergency call your local emergency number (112 in India and Europe, 911 in the US). AI Cure Terms of Use · Privacy