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Cycling-Based Aerobic Exercise Intervention for Individuals With Chemotherapy-Induced Peripheral Neuropathy (CIPN)

RecruitingNAAges 18 Years - anyAllUniversity of Alberta
NCT07150117 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

CYCLE-CIPN is a proof-of-concept study designed to evaluate whether a prescribed aerobic exercise intervention has the potential to reduce the symptoms and functional impact of CIPN. The small number of participants in the proposed study will allow us to make decisions on the feasibility ("go/no-go") of a future larger-scale trial. The protocol will assess feasibility and acceptability through recruitment, completion, adherence, program satisfaction, and safety. The study will also evaluate CIPN symptoms using both patient-reported and objective outcome measures, as well as fitness and quality of life outcomes. We aim to recruit 30 participants. The Health Research Board of Alberta Cancer Committee has approved this study. Participants will participate in a stationary cycling-based aerobic exercise program biweekly for 12 weeks. Exercise sessions will be supervised and progressive, bet

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📋 Eligibility rules (as published)
Inclusion Criteria: * 18 years or older * Cancer diagnosis stage I to III * CIPN: grade 1 (mild) * Receiving or have received chemotherapy treatment for cancer * Speak, read and understand English Exclusion Criteria: * Medical conditions that cause additional neuropathy symptoms (i.e. diabetes) * Any uncontrolled medical conditions * Will undergo surgery or radiation therapy during the study period * Are already receiving an aerobic exercise training program * Are already participating in an exercise-based research study * Are unable to provide signed informed consent
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What it tests

  • Exercise
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Where

1 site
Cross Cancer Institute
Edmonton, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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