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Phase 1/2 Study to Evaluate TH9619 in the Treatment of Advanced Solid Tumors

RecruitingPhase 1, Phase 2Ages 18 Years - anyAllOne-carbon Therapeutics AB
NCT07151040 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This is a first in human, multi-center, open-label, dosage escalation study to determine the recommended dose range of TH9619 in subjects with advanced cancer.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Must have given written informed consent * Histopathologically confirmed advanced cancer (colorectal cancer, head and neck squamous cell cancer, non-small cell lung cancer and gastric cancer (including gastroesophageal junction cancer)) * Prior treatment with at least one line of cytotoxic systemic therapy for metastatic/unresectable cancer * Adult patients (≥18 years of age) * Must be willing to comply with study procedures Exclusion Criteria: • History or presence of any clinically significant disorders as judged by the Investigator.
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What it tests

  • TH9619
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Where

4 sites
Institut Gustave Roussy
Villejuif, France
Vall D Hebron Institute Of Oncology
Barcelona, Spain
Hospital Universitario Fundacion Jimenez Diaz
Madrid, Spain
Newcastle University
Newcastle upon Tyne, United Kingdom
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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