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โ† Trials
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Effects of Resistance Exercises in Hereditary Sensory-Motor Neuropathy (Charcot-Marie-Tooth Disease)

RecruitingNAAges 15 Years - 29 YearsAllUniversidad de La Frontera
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to compare the effects of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals aged 15 to 29 years, with and without Hereditary Sensorimotor Polyneuropathy (HSPN). The main questions to answer are: What is the effect of an 8-week resistance exercise training program on skeletal muscle quality, functional capacity, and quality of life in young individuals with and without HSPN? Will the percentage of improvement after the program be greater in participants with HSPN compared to those without, due to greater baseline alterations? Researchers will compare the resistance exercise training program with baseline conditions to determine its effectiveness in improving skeletal muscle quality, functional capacity, and quality of life. Participants will undergo a supervised l

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Men or women between 15 and 29 years of age with a diagnosis of hereditary sensorimotor polyneuropathy (HSPN) in any of its subtypes, living in the community (for experimental group). * Healthy men or women between 15 and 29 years of age living in the community (for control group). * Having active ankle movement within a range from plantarflexion to at least 0ยฐ of ankle dorsiflexion, allowing for strength training. Exclusion Criteria: * Osteoarticular or mobility impairments that prevent safe performance of resistance exercise training (e.g., ankle arthrodesis). * Use of nutritional supplements that may affect skeletal muscle regulation (leucine, glutamine, casein, whey protein, fatty acids, creatine, among others). * Untreated and/or uncontrolled chronic diseases or intellectual disability. * History of surgery * Participation in a resistance exercise training program within the past 6 months.
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What it tests

  • Progressive Resistance Exercise Training
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Where

2 sites
Temuco, Chile
Temuco, Chile
Universidad de La Frontera
Temuco, Chile
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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