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Persistence of Immune Response Six Years After One Dose of 9vHPV Vaccine Among Male and Female Students

RecruitingPhase 4Ages 15 Years - 17 YearsAllCanadian Immunization Research Network
NCT07156084 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Since the 2019-2020 school year, the province of Quebec (Canada) has been administering one dose of nonavalent (9vHPV) vaccine to students of all genders in Grade 4 of elementary school through the school-based program. Little data on the immunogenicity (antibody production) and long-term efficacy of a single dose of the vaccine are available, particularly in boys. The primary objective of this study is to assess the persistence of HPV antibodies six years after the administration of a single dose of the 9vHPV vaccine to students aged 9 to 11 years in Grade 4 in 2019-2020. The study will be conducted at the CHU de Québec-Université Laval research center. Recruitment is conducted through school service centers in the Quebec City region. Youth who received only a single dose of the 9vHPV vaccine at the ages of 9-11 in 2019-2020 will be eligible to participate. Approximately 300 youth

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📋 Eligibility rules (as published)
Inclusion Criteria: * Have received a single dose of 9vHPV vaccine at ages 9-11 during the school year 2019-2020; * Not have received any other HPV vaccine doses; * Be able to consent to the study. Exclusion Criteria: * Immunosuppressed (at recruitment or when immunized).
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What it tests

  • HPV nonavalent vaccine (Gardasil-9)
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Where

1 site
Centre de recherche du CHU de Québec-Université Laval
Québec, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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