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HIV Prevention With PrEP Among People on Opioid Replacement Therapy

RecruitingPhase 4Ages 16 Years - anyAllCara Spence
NCT07160075 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

The purpose of this study is to assess the feasibility and acceptability of providing oral pre-exposure prophylaxis (PrEP) and opioid agonist therapy (OAT) simultaneously in existing pharmacy-based programs operating in Alberta and Saskatchewan, to collect preference, adherence, and persistence data on oral PrEP, and to assess interest / acceptability of long-lasting injectable options for human immunodeficiency virus (HIV) prevention.

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📋 Eligibility rules (as published)
Inclusion Criteria: * HIV negative * Ongoing behaviors with potential HIV exposure as assessed by a clinician * Regularly engaged with their respective OAT program at least 3 days a week for the past 2 weeks * Report willingness to return for follow-up visits Exclusion Criteria: * Creatine clearance \<30 mL/min or any medical condition or medication known to be contraindicated with the use of Emtricitabine/Tenofovir Alafenamide (F/TAF) or Emtricitabine/Tenofovir Disoproxil Fumarate (F/TDF) * Taken PrEP within the last 24 hours at the time of screening or enrollment * Deemed appropriate by a clinician for HIV Post-Exposure Prophylaxis at the time of screening or enrollment
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What it tests

  • Simultaneous administration of OAT and oral PrEP at existing pharmacy-based programs
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Where

6 sites
Sheldon M Chumir Health Centre
Calgary, Canada
Queen City Wellness Pharmacy
Regina, Canada
Mayfair Drugs Pharmacy
Saskatoon, Canada
Pharmasave Riversdale Pharmacy
Saskatoon, Canada
The Medicine Shoppe Pharmacy
Saskatoon, Canada
Meadowgreen Pharmacy
Saskatoon, Canada
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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