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Vaginal Estrogen Treatment and Effect on Hemostatic Parameters in Postmenopausal Women

RecruitingPhase 4Ages 50 Years - anyFemaleUniversity of Aarhus
NCT07160504 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This study investigates whether vaginal estrogen treatment has an effect on hemostatic parameters in postmenopausal women. Blood samples are collected before and after 3 months treatment to assess changes in hemostasis.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Postmenopausal women aged ≥ 50 * Symptomatic vaginal atrophy * Indication for standard treatment with vaginal estrogen tablets 10 µg at least three times a week * Study population 1: without a history of venous thromboembolic event * Study population 2: with a history of venous thromboembolic event Exclusion Criteria: * Unable to give written informed consent * Does not speak Danish * Current cancer treatment * Current treatment with blood thinning medication (except plateletinhibitor) * Current treatment with local or systematic estrogen * Systemic inflammatory disease, liver disease or kidney disease
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What it tests

  • Vaginal estradiol tablets
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Where

1 site
Department of Obstetrics and Gynecology, Aarhus University Hospital, Denmark
Aarhus N, Denmark
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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