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โ† Trials
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Letrozole Plus Misoprostol Versus Misoprostol Alone for Treating Women With Missed Miscarriage

RecruitingPhase 4Ages 18 Years - 45 YearsFemaleNishtar Medical University
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In plain words

What the trial is, and whether it could suit you

The goal of this clinical trial is to learn whether adding the medicine letrozole to Misoprostol helps women have a complete abortion more often than using Misoprostol alone for the treatment of missed miscarriage (when a pregnancy has stopped developing but has not yet passed naturally). The main questions this study aims to answer are: 1. Does taking letrozole for 3 days before misoprostol increase the chance of a complete abortion compared to misoprostol alone? 2. Does the use of letrozole affect the time it takes for abortion to occur? Who can Join? i. Women up to 13 weeks of pregnancy (based on last menstrual period and confirmed by ultrasound) who have a missed miscarriage. ii. Only those with a single pregnancy are eligible. iii. Women with a previous cesarean section or uterine scar are not included. What Will Happen in the Study A total of 92 women will take part. Participa

Sign in to get the eligibility rules as simple questions to take to your doctor.

๐Ÿ“‹ Eligibility rules (as published)
Inclusion Criteria: * Pregnant women up till 13th weeks of gestation according to last menstrual period (LMP) dates, confirmed on ultrasound * Single intrauterine pregnancy * Planned for termination due to missed miscarriage Exclusion Criteria: * Previous history of cesarean section * Uterine scar due to previous procedure like myomectomy
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What it tests

  • Misoprostol (given vaginally)
  • Letrozole 5 mg
  • Placebo
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Where

1 site
Nishtar Medical University and Hospital
Multan, Pakistan
๐Ÿค Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible โ€” always decide together with your own doctor.
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