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Postural Mobilization Compared to Noradrenaline Only in Off-Pump CABG Surgery

RecruitingNAAges 18 Years - anyAllInfirmerie Protestante de Lyon
NCT07163858 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

This interventional prospective randomized study is designed to compare hemodynamic management using postural mobilization (+/- noradrenaline) versus noradrenaline only in patients undergoing open-heart coronary artery bypass graft (CABG) surgery.

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📋 Eligibility rules (as published)
Inclusion Criteria: * Adult patient * patient requiring isolated coronary bypass surgery * Elective procedure or medical emergency * First cardiac surgery * Patient with an EF ≥30% * Mandatory affiliation to a social security system * Signed informed consent form * Suspension of renin-angiotensin system inhibitors and angiontensn-neprilysin receptor blockers and sartans the day before surgical procedure Exclusion Criteria: * Contraindication to an inotropic substance (only NA will be used) * Contraindication to passive leg raising * Patient in a life-threatening emergency * History of cardiac surgery * Bilateral iliac or common femoral artery occlusion * EF \< 30% * Pregnancy and breastfeeding * Renal failure (GFR \< 40 ml/min/1.73 m²) * Patient with bilateral thigh amputation * Class III obesity BMI \> 40 kg/m²
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What it tests

  • passive leg raising for hemodynamic management during open-heart coronary bypass grafting
  • Use of Noradrenaline only in control group
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Where

1 site
Infirmerie Protestante de Lyon
Caluire-et-Cuire, France
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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