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Association of POCD With Circulating Biomarkers in Patients Undergoing TUR of Bladder Tumor

Recruitingn/aAges 18 Years - 80 YearsAllOsijek University Hospital
NCT07165236 on ClinicalTrials.gov ↗
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In plain words

What the trial is, and whether it could suit you

Bladder tumor is one of the most widespread tumors in the world, with increasing prevalence at the global level. One of the procedures in patients with bladder tumors is transurethral resection of the bladder (TURM) most often performed endoscopically under general anesthesia. This patient population has certain characteristics in common. One of them is exposure to common risk factors for the formation of bladder tumors, such as aniline dyes and solvents. These substances are associated with the onset of neurodegeneration and oxidative stress. Smoking is another factor that affects the formation of bladder tumor. A significant part of patients with bladder tumor are an elderly population, which is repeatedly exposed to surgical procedures, with numerous comorbidities, with a high risk of postoperative complications and the development of perioperative cognitive deficits, which can furthe

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📋 Eligibility rules (as published)
Inclusion Criteria: * adult patients from 18-80 years, * elective operations of tumor bladder cancer (TUR), * patients can communicate, * patients who can sign the information consent and questionnaires Exclusion Criteria: * patients under the age of 18, * patients above 80 years, * patients who are unable to communicate * patients who do not understand informed consent for the research, * patients who are unable to write * emergency surgery, * patients with proven hypersensitivity to some of the drugs used in the study * patients in a state of shock, septic, or hemorrhagic patients with neurodevelopmental disorders
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What it tests

  • Not listed
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Where

1 site
Osijek UH
Osijek, Croatia
🤝 Taking part is your choice, and you can leave at any time. Only the trial team can confirm you are eligible — always decide together with your own doctor.
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